This site contains information about the emerging field of genetically encoded sensors of cellular membrane electrical potential. These sensors are engineered protein constructs that can be expressed in cells from cDNA. They allow scientists to monitor the electrical status of a living cell using fluorescence light measurements. In these pages are:

  • Information about how such probes function
  • A place to order the cDNA for these experimental probes
  • Experimental results on how these probes function in cell lines and neurons.

This site is a continual work in progress. This work is funded by a
National Institutes of Health grant (U24NS057631, DC005258-39, ARRA U24NS057631-03S1, ARRA-R01NS065110 and R01 NS083875-01) and The John B. Pierce Laboratory, Inc.

*Legal Issues: The information contained in this site is for research purposes only and should not be used in human investigations. This information is copyrighted by the author of this site (Vincent Pieribone) and represents the views and opinions of the author and not those of any affiliated or non affiliated institutions or persons.